STRUCTURAL ASPECTS OF HUMAN ERYTHROCYTE AUTOANTIBODIES
نویسندگان
چکیده
منابع مشابه
Structural Aspects of Human Erythrocyte Autoantibodies
The 7S gamma-globulins causing erythrocyte autosensitization in 20 patients were isolated by elution and examined for homogeneity or heterogeneity of their L chain types and electrophoretic dispersion. The isolated erythrocyte autoantibodies from 12 patients contained only 1 detectable L chain type. Two of these "monotypic" populations showed appreciable restriction of electrophoretic dispersio...
متن کاملThe Production of Erythrocyte Autoantibodies in Chimpanzees
Young adult chimpanzees immunized with human blood products produced circulating antibodies which reacted with human red cells of a certain proportion of chimpanzees. In addition, agglutinins were formed which reacted with the animals' own erythrocytes. That these agglutinins were true autoantibodies was demonstrated by: (a) their ability to sensitize the animals' own erythrocytes at 37 degrees...
متن کاملErythrocyte autoantibodies, autoimmune haemolysis, and myelodysplastic syndromes.
Immunohaematological investigations were carried out in 46 patients with erythrocyte autoantibodies associated with myelodysplastic syndromes. Eight patients had refractory anaemia, 17 refractory anaemia with ring sideroblasts, 11 refractory anaemia with excess of blasts, four chronic myelomonocytic leukaemia, five refractory anaemia with excess of blasts in transformation and one could not be ...
متن کاملErythrocyte autoantibodies, autoimmune haemolysis, and carcinoma.
AIMS To examine a large series of patients in whom both red cell autoantibodies and carcinoma are present; and to determine whether this rare occurrence is a true association or a chance event. METHODS The laboratory records of 160 patients (76 men, 84 women; mean age 68 years) with erythrocyte autoantibodies and confirmed carcinoma were examined for site of tumour origin and clinical and imm...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1965
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.121.1.1